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    The burden of HIV-related admissions and mortality at Princess Marina Hospital, Botswana in 2000: a pre-combination antiretroviral therapy era

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    Molefi_SR_2017.pdf (323.3Kb)
    Date
    2017-03-31
    Author
    Molefi, Mooketsi
    Tshikuka, Jose-Gaby
    Monagen, Tuduetso Leka
    Magafu, Mgaywa Gilbert Mjungu Damas
    Masupe, Tiny
    Mbongwe, Bontle
    Rheeder, Paul
    Publisher
    Scientific Research, www.scirp.org/
    Link
    http://file.scirp.org/Html/7-5200375_75096.htm
    Type
    Published Article
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    Abstract
    Background: human immune virus and acquired immunodeficiency syndrome (HIV/AIDS) have been recognized in Botswana for the last three decades, however, combination anti-retroviral therapy (cART) was only introduced after 2000. Facility-based historical data of the burden of HIV/AIDSrelated conditions pre-cART have so far not been analyzed. Objective: To analyze the burden of HIV-related admissions and HIV-related deaths, and identify the socio-demographic factors associated with HIV/AIDS deaths at Princess Marina Hospital (PMH) in the year 2000. Methods: A retrospective review of medical files was carried out between May and June 2014. Nine thousand seven hundred and forty-six (9746) records were analyzed for the year for 2000. Cases were identified as documented HIV/AIDS as per medical notes and/or documentation of any of the conditions listed in sections B20- B24 of the International Classification of Diseases (ICD 10 B20-B24). Outcomes were the percentages of HIV-related admissions and HIV-related deaths out of all admissions and deaths. The in-hospital case fatality rate (CFR) was also calculated. Log-binomial regression models were used to determine the most significant factors associated with HIV-related admission and death. Results: The percentages of HIV-related admissions and HIV-related deaths were 4.1% (403/9746) and 11.3% (80/707), respectively. The in-hospital HIVCFR was 19.9% (80/403). Adjusted log-binomial models identified the most
    URI
    http://hdl.handle.net/10311/1767
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    • Research articles (Dept of Electrical Engineering) [18]

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